Author Archives: the ligand binding-assay.com team

No RNA Extraction: Real-Time RT-qPCR Works Anyway!

Hi all, welcome back to our bioanalytical ligand binding assay album for the Biotechnology scene. Today we would like to point you to the outstanding Merck & Co paper collection on siRNA drug development research. The major finding of Wang … Continue reading

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RNActive® Vaccines Complexed to Protamine

Dear all, numerous research activities with a strong focus on nucleic acid chemistry-based therapeutics have to face the same problem: how to transport these poly-anionic compounds into the cell? The most applied technology is the complexation of siRNA (1), microRNA … Continue reading

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Solid Phase vs. Liquid Phase Ligand Capturing

As in real life, often there are different ways to get the same result. Almost the same, I´d better say, because for the bioanalytical ligand binding assay developer it is indeed a difference whether the ligand is captured in the … Continue reading

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Upcoming Drugs: In Vivo Gene Transfer With Messenger RNA

Dear all, the world of nucleic acid therapeutics is fascinating. A novel advancement in this field develops messenger RNA as a tool for in vivo gene transfer, either for antigen expression in vaccination procedures, or to improve, and even supplement … Continue reading

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Haemolytic Uremic Syndrome (HUS) Epidemy in Germany

Dear all, for all people living outside Germany you probably might not came across the HUS outbreak in the north of Germany, caused by multidrug resistant enterohaemorrhagic Escherichia coli (EHEC) strain O104:H4. The dramatic epidemy caused 29 deaths (as of … Continue reading

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