Monthly Archives: May 2011

2´-O-Methyl RNA Does Not Hamper Reverse Transcription

Dear all, today we added some thoughts on the influence of 2´-O-methyl modifications on the reverse transcription of RNA to our blog. This modification generally does influence the reaction, but reliable quantification is still possible. Remember that piwi-interacting RNA (piRNA) … Continue reading

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Small RNA Drugs Update: hairpin, piwi, micro, whatever

Dear all, sorry for the delay, but now we finally managed to get you an impression of which tools the RNA world keeps for us to turn into novel therapeutics. Also, we added some interesting Argonaute liquid phase ligand binding … Continue reading

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ELISpot Improvement is Our Paper of April 2011

Dear all, who will come off as the winner of our ‘Paper of the Month’ Challenge? Well, we just decided to award (the honour to be published here) to a great improvement for the development of novel and specific human … Continue reading

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Miravirsen (microRNA-122 Antagomir) Update

Dear all, welcome back to our ligand binding assay album. The collection is growing and growing, today we added the Miravirsen story ( a 15mer microRNA-122 antagomir for Hepatitis C treatment) here; also, we introduced the fascinating Luminex bead assay … Continue reading

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ELISpot assay with IFN-gamma as the ligand

Dear all, one of the most common multiplate assays to monitor immune response e.g. of peripheral T cells ist the ELISpot ligand binding assay, read more if you are interested. Have a lovely weekend, your binding-assay.com team.

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